Dr. Sayer believes that the new drug that Leonard Lowe is taking is harming him. He feels that the medicine is causing his catatonia. Leonard's impaired motor skills illustrate catatonia.

Temple, an autistic student, watches a short film on optical illusions and is immediately intrigued by it. She sets out to achieve the effects in the movie and does so after much persistence.

The doctor explains to Stephen Hawking that Motor Neuron Disease is affecting his ability to use any muscle activity, such as speaking, walking, breathing, and swallowing. The signals that tell the muscles to move are disrupted, and the result is gradual muscle decay.

Charlie and Ray are at a restaurant for breakfast, and Ray irritates Charlie with his repetitive behavior. Ray states that he needs his toothpicks even though he will be eating pancakes. He also demonstrates his savant memory by matching the waitress' name to her phone number in the phone book.

Temple attends a National Autistic Convention and speaks out about autism. The audience enjoys her insight on the topic so much that she is asked to take the stage and speak.