The group takes a boat ride through the small intestine, where the workers are not only singing about the intestine but are also part of an assembly line that illustrates the small intestine's function: the digestion and absorption of food.
While in the middle of its boat ride, the group encounters the sexually transmitted infection, gonorrhea. Before destroying gonorrhea with a lit match, Poncho alludes to a symptom of the infection: a burning sensation during urination.
In this emotional clip, Josie Webb gives a speech about her life, youth, and perceived immortality. In her speech, she explains how she got AIDS, and one of her classmates states that she doesn't understand how Josie could get the disease. The other classmates clarify the misconceptions about HIV and AIDS.